Otorrinolaringologia Vicente Diamante Pdf

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Conclusion: There were no apparent differences in speech performance after cochlear implantation between patients with biallelic GJB2 and/or GJB6 mutations and those with deafness of unknown aetiology. These data have important implications for the selection of prognostic indicators of the outcome of cochlear implantation. Objective: To compare performance after cochlear implantation in children with mutations in GJB2 (connexin 26) and/or GJB6 (connexin 30) and children with deafness of unknown aetiology. Subjects and methods: Genetic analysis and speech performance evaluation was determined in 24 patients with (n=11) and without (n=13) biallelic GJB2 and/or GJB6 mutations who underwent cochlear implantation. Speech perception skills were measured 12 and 24 months after surgery. Each patient was classified in accordance with the speech perception category (SPC). Results: Overall, the two groups showed similar significant improvement in speech perception after implantation.

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Keywords:GJB2, connexin 26, GJB6, connexin 30, hearing loss, deafness, cochlear implant, speech perception

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Revista de otorrinolaringología y cirugía de cabeza y cuello

On-line version ISSN 0718-4816

DIAMANTE, Vicente Guillermo and PALLARES, Norma.Auditory brainstem implant in children. Rev. Otorrinolaringol. Cir. Cabeza Cuello [online]. 2007, vol.67, n.3, pp.244-249. ISSN 0718-4816. http://dx.doi.org/10.4067/S0718-48162007000300006.

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